By Shayne C. Gad
Acute toxicology trying out offers the 1st defensive position opposed to in all probability harmful chemical compounds. This publication is a whole and useful consultant to carrying out and examining all regulatory required and widely used acute toxicity assessments. It offers particular protocols for all the universal attempt designs and stories their improvement and pursuits. Acute Toxicology trying out, moment Edition will curiosity not just staff within the pharmaceutical undefined, but additionally researchers and scholars in toxicology and public health.
* Over a hundred tables summarizing and reading results
* entire insurance of all significant try designs and their barriers and advantages
* present prestige of different try out designs and types
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Additional resources for Acute Toxicology Testing
Presented at the NATO Advanced Research Workshop, Pharmaceutical Application of Cell and Tissue Culture to Drug Transport, Bandol, France, September 4-9. Boyce, S. , Hansbrough, J. , and Norris, D. A. (1988). Cellular responses of cultured human epidermal keratinocytes as models of toxicity to human skin. In Progress in in Vitro Toxicology (A. M. ), pp. 23-37. Liebert, New York. , and Lippold, B. H. (1982). Dermal and Transdermal Absorption. Wissenschaftliche Verlagsgesellschaft, Stuttgart. Bronough, R.
II. , separate major variable to be studied): - - H o w is the variable of interest to be measured? - - W h a t is the nature of the data generated by the measure? Are we getting an efficient set of data? )? - - A r e there possible interactions between measurements? Can they be separated/identified? w I s our N (sample size) both sufficient and efficient? J W h a t is the controlmformal or informal? Is it appropriate? - - A r e we needlessly adding confounding variables (asking inadvertent or unwanted questions) ?
Vol. 5. Liebert, New York. , Akers, W. , McCreesh, A. , and Maibach, H. I. (1975).