
By Herbert F. Bender
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Additional resources for Das Gefahrstoffbuch
Sample text
Während teratogene Effekte anatomische Missbildungen ausdrücken, ist der Begriff Fruchtschädigung weiter gefasst. Hierzu zählen alle durch die Stoffexposition ausgelösten Veränderungen, die bei der Geburt erkennbar sind, wie z. B. verringertes Geburtsgewicht oder Organschäden. Der Begriff Entwicklungsschädigung (nach EU-Definition) umfasst darüber hinaus alle schädlichen Wirkungen auf die Entwicklung der Nachkommen, die während der Schwangerschaft verursacht werden und sich prä- oder postnatal (vor oder nach der Geburt) bis zur Pubertät manifestieren.
Stress, Stoffe) und durch innere Faktoren (z. B. psychische Schwankungen) beeinflusst. Auswirkungen auf die Spermatogenese (Heranreifen der Spermien) sind auf vielfältige Art möglich; die Wirkung von Alkohol, Rauchen oder Drogen ist eindeutig belegt, desgleichen können auch Chemikalien entsprechende Effekte auslösen. Im Gegensatz hierzu sind die Ovarien deutlich besser gegen Fremdeinflüsse geschützt, wenngleich auch hier exogene Schäden denkbar sind. 8 Krebserzeugende Wirkung Tumore werden durch unkontrolliertes Zellwachstum ausgelöst.
Peto [6] eine umfangreiche Studie über die Krebsursachen in den westlichen Industrienationen durchgeführt. Zahlreiche zwischenzeitlich realisierte Untersuchungen, z. B. vom Krebsforschungszentrum Heidelberg [7], kommen zu grundsätzlich ähnlichen Ergebnissen. 9 stellt diese Ergebnisse grafisch dar. Mit einem Anteil von ca. 65 % nehmen die „freiwilligen“ Krebsursachen „Rauchen“ und „falsche Ernährung“, insbesondere zu fettreiche Überernährung, eine dominierende Stellung ein, gefolgt von der endogenen Ursache Vererbung.