Early Nutrition: Impact on Short- and Long-Term Health by H. van Goudoever, S. Guandalini, R.E. Kleinman

By H. van Goudoever, S. Guandalini, R.E. Kleinman

During this publication, a particular workforce of overseas specialists evaluation dietary practices and feeding behaviors in infancy and early formative years. They current the most recent wisdom on feeding practices in the course of the interval thought of and their impact on development, improvement, and rapid and long term overall healthiness. one of many major themes mentioned consists of feeding practices within the child severe care unit, targeting using human donor milk and probiotics within the nutrition of untimely and sick newborns. one other aspect of concentration is the explanations and the impression of an inadequate consumption of chosen micronutrients, reminiscent of iron and zinc, that's hugely commonly used fairly within the constructing global. in addition to, this ebook comprises info at the effect of early feeding behavior at the later improvement of a couple of health-related concerns reminiscent of nutrition asthma, later foodstuff personal tastes and consuming conduct, weight problems, bone improvement, the chance of constructing celiac illness in genetically predisposed little ones. This quantity presents crucial studying for pediatricians, scientific investigators and medical examiners drawn to the results of early food on overall healthiness.

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Additional info for Early Nutrition: Impact on Short- and Long-Term Health (Nestle Nutrition Workshop Series: Pediatric Program)

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Vevey/S. E. H. A. B. van Goudoevera–c aDepartment of Pediatrics, Sophia Children’s Hospital, Erasmus Medical Center, Rotterdam, of Pediatrics, Emma Children’s Hospital, Amsterdam Medical Center, and cDepartment of Pediatrics, VU University Medical Center, Amsterdam, The Netherlands bDepartment Abstract Amino acids and proteins play a pivotal role during growth and development. Besides acting as building blocks during tissue synthesis, amino acids or proteins act specifically by upregulating defense systems or by stimulating key sites in metabolic pathways.

16 Elias SL, Innis SM: Infant plasma trans, n-6, and n-3 fatty acids and conjugated linoleic acids are related to maternal plasma fatty acids, length of gestation, and birth weight and length. Am J Clin Nutr 2001;73:807–814. 17 Innis SM, King DJ: Trans fatty acids in human milk are inversely associated with concentrations of essential all-cis n-6 and n-3 fatty acids and determine trans, but not n-6 and n-3, fatty acids in plasma lipids of breast-fed infants. Am J Clin Nutr 1999;70:383–390. 18 Farquharson J, Jamieson EC, Abbasi KA, et al: Effect of diet on the fatty acid composition of the major phospholipids of infant cerebral cortex.

During short time windows in development, hormones and key metabolic cues are believed to play important roles in establishing the set point for receptor pathways and control of gene expression. Although it is known that the dietary ␻-6 and ␻-3 fatty acids impact ␻-6 and ␻-3 fatty acids in the developing brain and liver as shown in figure 2, little is as yet known with regard to the potential programming of neural feeding circuitry or metabolic development in the liver. Mathai et al. [24] have provided evidence of long-term effects of ␻-3 fatty acid deficiency in gestation and lactation on feeding behavior in rats.

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