Endocrine Disruptors 2012 by iSmithers

By iSmithers

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Substances with endocrine properties are also subject to authorization under the REACH Regulation (1907/2006). However, there is currently no agreed guidance on how to identify and evaluate endocrine activity and disruption. Several Individual Member states including Germany, UK, and Denmark have been preparing schemes and evolving approaches to define the issues and make recommendations. However these have to be accepted and incorporated into the appropriate EU guidance documents. 3. Commission Activities In December 1999, the Commission adopted a Communication to the Council and European Parliament on a Community Strategy for Endocrine Disrupters.

Having the same levels of concern as substances identified as C, M, R category 1 or 2, PBT or vPvB substance. •However No internationally agreed methodologies or criteria available for endocrine disrupting properties (ECHA Guidance for SVHC) •Priority of inclusion of EDC substances in Annex XIV be given to substances with a wide dispersive use or are manufactured or imported in high volumes •Decision for inclusion in Annex XIV will be based on available information and a weight of evidence approach will be used 05 January 2012 Paper 4 - Neale Page 14 of 26 pages Endocrine Disruptors 2012 14-15 February 2012 – Munich, Germany Slide 23 EU’s current and future legislative and regulatory REACH – Regulation (EC) No 1907/2006 framework – Pesticides (2) 05 January 2012 Slide 24 Commission Strategy on Regulating EDs • In 1996, the European Commission implemented a policy as to the use and regulation of suspected endocrine disturbing substances, and, in December 1999, it adopted a Community Strategy for Endocrine Disrupters.

A work shop was held to discuss the report; the Paper 4 - Neale Page 2 of 26 pages Endocrine Disruptors 2012 14-15 February 2012 – Munich, Germany outcome of which was published in 2011. However, it was recognized that further work was needed, especially concerning the relevance to man of the endocrine mechanism of toxicity and the population relevance of the observed related effects for ecotoxicological assessment. In May 2011, a further workshop to discuss” the Risk assessment of endocrine disrupting chemicals” was held in Florence.

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