Handbook of Neurochemistry and Molecular Neurobiology: by Katsuhiko Mikoshiba, Abel Lajtha

By Katsuhiko Mikoshiba, Abel Lajtha

This quantity of the instruction manual of Neurochemistry and Molecular Biology makes a speciality of molecular occasions serious about synapse formation, synaptic plasticity and ongoing neural job. the amount explores axonal progress cones, synapse improvement, and mechanisms of LTP and LTD, and calcium dynamics. specific realization is given to operate and trafficking of membrane proteins together with numerous ion channels, aquaporines, hole junctions.

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Additional resources for Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms (Springer Reference)

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J Neurosci 24: 286-296. Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, et al. 2005. Ptf1a a bHLH transcriptional gene defines GABAergic neuronal fates in cerebellum. Neuron 47: 201-213. Kuemerle B, Zanjani H, Joyner A, Herrup K. 1997. Pattern deformities and cell loss in Engrailed-2 mutant mice suggest two separate patterning events during cerebellar development. J Neurosci 17: 7881-7889. Landsberg RL, Awatramani RB, Hunter NL, Farago AF, DiPietrantonio HJ, et al. 2005. Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.

J Biol Chem 282: 303-318. Scheid MP, Woodgett JR. 2001. PKB/AKT: Functional insights from genetic models. Nat Rev Mol Cell Biol 2: 760-768. Schmidt A, Hall A. 2002. Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch. Genes Dev 16: 1587-1609. Schwamborn JC, Puschel AW. 2004. The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 7: 923-929. Shi SH, Jan LY, Jan YN. 2003. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity.

4 Neuronal Polarity-Regulating Molecules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PI3-kinase/Akt/GSK-3b Pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Regulation of CRMP-2 by GSK-3b . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Positive Feedback Loop . . . . . . . . . . . . . .

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