By Katsuhiko Mikoshiba, Abel Lajtha
This quantity of the instruction manual of Neurochemistry and Molecular Biology makes a speciality of molecular occasions serious about synapse formation, synaptic plasticity and ongoing neural job. the amount explores axonal progress cones, synapse improvement, and mechanisms of LTP and LTD, and calcium dynamics. specific realization is given to operate and trafficking of membrane proteins together with numerous ion channels, aquaporines, hole junctions.
Read Online or Download Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms (Springer Reference) PDF
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Additional resources for Handbook of Neurochemistry and Molecular Neurobiology: Neural Signaling Mechanisms (Springer Reference)
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J Biol Chem 282: 303-318. Scheid MP, Woodgett JR. 2001. PKB/AKT: Functional insights from genetic models. Nat Rev Mol Cell Biol 2: 760-768. Schmidt A, Hall A. 2002. Guanine nucleotide exchange factors for Rho GTPases: Turning on the switch. Genes Dev 16: 1587-1609. Schwamborn JC, Puschel AW. 2004. The sequential activity of the GTPases Rap1B and Cdc42 determines neuronal polarity. Nat Neurosci 7: 923-929. Shi SH, Jan LY, Jan YN. 2003. Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity.
4 Neuronal Polarity-Regulating Molecules . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PI3-kinase/Akt/GSK-3b Pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Regulation of CRMP-2 by GSK-3b . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Positive Feedback Loop . . . . . . . . . . . . . .