Induction of Thyroid Cancer by Ionizing Radiation (N C R P by National Council on Radiation Protection

By National Council on Radiation Protection

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Additional resources for Induction of Thyroid Cancer by Ionizing Radiation (N C R P Report)

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N (4-3) In applying Eq. 19. 4 million person-rad-years with an estimated spontaneous rate of clinically detectable thyroid cancer of about 3. 69 cases per million person per rad per year for children and adults respectively. 05. In fact, no excess cancers were determined to be present. The calculation in the case of children is less certain due to the small numbers and lack of precise information regarding their actual spontaneous rate of thyroid cancer as they reach adult life. Thus, in summary, I3'I appears less carcinogenic in people on a radfor-rad basis than external radiation.

However, adequate information often does not exist for such calculations. 7). 2), then the resultant proportional incidence is identical to that which would be predicted for a non-Jewish, Caucasian population comprised equally of both sexes (72 percent of projected ineidence for non-Jewish, white women). 1 would appear to be applicable to a non-Jewish, Caucasian population comprised equally of both sexes and might overestimate the risk in black Americans while underestimating the risk in Jewish Americans.

5 for adenomas; 111 for carcinomas 94-1060 rads 1/20 750-3000 R 115at low doses; 100-1800 rads 1115-1/30 a t high doses 6400-16,000 rads 2200- 11,000 rads 80-850 rads . 24,000-90,000 rads 530-51,000 rads Z t 4 $ 8E Hundreds to tens of thousands of rads Klassovskii et al. (1970) Rat and Dog Histologic, functional changes l/lO-1/25 Walinder & Sjoden (1971) Walinder & Sjoden (1972) Walinder et al. (1972) Mouse Inhibition of goitrogenesis Thyroid gland growth Inhibition of goitrogenesis 1/2-1/4 1500 rads 115-1/10 180 rads 1000-14,000 rads 1500-2000 rads Not stated but suggests x-ray and 1-132 about the same 1/9 1000-1500 rads 40005000 rads Book et al.

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