Management of Periprosthetic Joint Infections (PJIs) by J.J. Chris Arts, Jan Geurts

By J.J. Chris Arts, Jan Geurts

Management of Periprosthetic Joint Infections (PJIs): administration of PJIs discusses periprosthetic joint an infection (PJI), a reasonably infrequent prevalence that's still essentially the most severe problems in joint substitute surgical procedure. complex interactions among the pathogen, the host, and the implant can lead to PJIs which aren't purely bodily devastating for the sufferer, but additionally financially crippling for future health gurus and insurance firms.

Actions taken to lessen the chance of PJIs could be super not easy for the orthopaedic group. therefore, new learn, that's particular during this entire booklet, is being undertaken to lessen and deal with those not easy infections.

  • Provides crucial heritage wisdom at the mechanisms and identity of PJIs
  • Dedicated chapters specialise in the complicated, yet important eccentricities among PJIs in numerous components of the body
  • Contains contributions from a mix of medical and educational specialists within the box, hence making sure balanced coverage

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Sample text

Implant-related infections are unfortunately a common seen complication. The infection rates of these procedures vary from less than 1% in primary total arthroplasty procedures to 5% in revision surgery and even up to 16% in trauma surgery after severe open fractures [3–5]. Implant-related infections are associated with high morbidity, high mortality, and high costs because these kind of infections are difficult to treat [6]. Major difficulties in treatment of these infections are the protective biofilms formed on the surface of the orthopedic implants by microorganisms resulting in natural defence against antibiotics and the natural host response.

69 (Suppl. 1) (2014) 37–40.  Duncan, Two-stage revision arthroplasty of the hip for infection using an interim articulated Prostalac hip spacer: a 10- to 15-year follow-up study, J. Bone Joint Surg. ) 91 (11) (2009) 1431–1437.  De Vecchi, Does dithiothreitol improve bacterial detection from infected prostheses? A pilot study, Clin. Orthop. Relat. Res. 470 (10) (2012) 2915–2925.  Romanò, Use of dithiothreitol to improve the diagnosis of prosthetic joint infections, J. Orthop. Res. 31 (11) (2013) 1694–1699.

Despite the effective bone regeneration of autografts and allografts, these methods are associated with some disadvantages, respectively, limited availability and donor morbidity in autograft procedures or disease transmission or bacterial infection in allograft procedures [37,38]. Therefore, the use and applicability of biomaterials, that is, bone graft substitutes, are becoming increasingly important. Concerning bone regeneration and biomaterials, biocompatibility, biodegradability, and mechanical properties are important and frequently used terms.

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