Mutagenicity. New Horizons in Genetic Toxicology by John A. Heddle

By John A. Heddle

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1948). Philos. Trans. R. Soc. London, Ser. A 241, 147. Horowitz, N. , Houlahan, M. , Hungate, M. , and Wright, B. (1946). Science 104, 233. 1/SCREENING CHEMICALS FOR MUTAGENICITY 33 ICPEMC Newsletter (1980). No. 3, Committee 1, B. J. Kilby, Chairman. Mutat. Res. 76, 217. "International Evaluation of Short-term Tests for Carcinogens" (1981). Report of the International Collaborative Program, (F. J. de Serres and }. ), Elsevier, North-Holland, Amsterdam. Lefevre, P. , and Ashby, J. (1981). Carcinogenesis 2, 927.

Weil, C. , and Maronpot, R. R. (1981). " Bushy Run Research Centre, Pittsburgh, Pennsylvania. Sram, R. , and Kuleslov, N. P. (1980). Arch. Toxicol. Suppl. 4, 11. Strong, L. C. (1945). Proc. Natl Acad. Sei. U. S. A. 31, 290. Strong, L. C. (1946). YaJe /. BioJ. Med. 18, 359. Tatum, E. L. (1947). Ann. N. Y. Acad. Sei. 49, 87. United Kingdom Environmental Mutagen Society (UKEMS) (1982). Collaborative Genotoxicity Trial. Mutat. Res. (1982) 100. Venitt, S. (1978). Mutat. Res. 57, 107. Von Seheufler, H.

Auramine 4. Azathioprine b 5. Beryllium and certain beryllium compounds 6. Carbon tetrachloride 7. Dimethylcarbamoyl chloride 8. Dimethyl sulfate 9. Ethylene oxide 10. Iron dextran 11. Oxymetholone 12. Phenacetin 13. Polychlorinated biphenyls (PCBs) α Compiled from Volumes 1-25 of the IARC Monographs on the Carcinogenic of Chemicals to Humans. b Added to IARC (1979c) by a subsequent working group at IARC. Risk carcinogenicity was provided by data from experimental animals. For those compounds, therefore, no comparison can be made between epidemiological and experimental data.

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