By Arnold Stern
Provides clinical scholars 500 questions, solutions, and factors to arrange for the pharmacology element of the USMLE Step 1. the recent version contains many new questions within the two-step scientific structure to simulate the USMLE Step 1.
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Extra resources for Pharmacology: PreTest Self-Assessment and Review
There are three distinct phases that characterize the time-action pattern of most drugs: (1) The time to onset of action is from the moment of administration (T on the figure that accom- 44 Pharmacology panies the question) to the time when the first drug effect is detected (U). (2) The time to reach the peak effect is from administration (T) until the maximum effect has occurred (W), whether this is above or below the level that produces some toxic effect. (3) The duration of action is described as the time from the appearance of a drug effect (U) until the effect disappears (Y).
For each description below, choose the component of the microsomal mixed-function oxidase system with which it is most closely associated: a. b. c. d. e. f. g. Nicotinamide adenine dinucleotide phosphate (NADPH) Cytochrome a Adenosine triphosphate (ATP) NADPH–cytochrome P450 reductase Monoamine oxidase (MAO) Cyclooxygenase Cytochrome P450 General Principles 31 34. A group of iron (Fe)-containing isoenzymes that activate molecular oxygen to a form that is capable of interacting with organic substrates 35.
B. c. d. e.