Toxicogenomics-Based Cellular Models. Alternatives to Animal by Jos Kleinjans

By Jos Kleinjans

Toxicogenomics-Based mobile Models is a special and beneficial reference for all educational researchers utilising toxicogenomic equipment with admire to animal checking out for chemical protection. This source deals state-of-the-art info at the software of toxicogenomics to constructing choices to present animal toxicity assessments. through illustrating the improvement of toxicogenomics-based mobile versions for serious endpoints of toxicity and supplying real-world examples for validation and knowledge research, this e-book offers an evaluate of the present nation of the sector, in addition to possibilities and demanding situations for the longer term. Written through well known overseas toxicological specialists, this e-book explores ‘omics expertise for constructing new assays for toxicity trying out and security evaluate and gives the reader with a targeted exam of different ability to animal testing.

  • Describes the state of the art in constructing toxicogenomics-based mobile versions for chemical-induced carcinogenicity, immunotoxicity, developmental toxicity, neurotoxicity and copy toxicity
  • Illustrates the way to validate toxicogenomics-based substitute try types and gives an outlook to societal and financial implementation of those novel assays
  • Includes an summary of present checking out tools and hazard review frameworks
  • Provides a real-world evaluation through articulating the present improvement and demanding situations in toxicogenomics whereas suggesting how one can stream this box forward

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