By John W. Finley and Daniel E. Schwass (Eds.)
content material: The effect of food on xenobiotic metabolism / D.E. Schwass and J.W. Finley --
period in-between nutritional instructions to reduce the danger of melanoma / Sushma Palmer --
The inhibition and advertising of cancers via folic acid, nutrition B₁₂, and their antagonists / Victor Herbert --
The impact of fermentable nutritional fiber at the disposition and toxicity of xenobiotics / J. Donald Debethizy and Robin S. Goldstein --
impression of nutritional fiber on xenobiotics / David Kritchevsky --
impression of nutritional elements on drug disposition in common human matters / Elliot S. Vesell --
loose radical involvement in power ailments and getting older : the toxicity of lipid hydroperoxides and their decomposition items / William A. Pryor --
Xenobiotic adduct formation with DNA or glutathione following oxidation by means of lipid peroxidation or hydrogen peroxide-peroxidase / M. Rahimtula, W. Marshall, B. Gregory, and P.J. O'Brien --
Antioxidants and malonaldehyde in melanoma / Raymond J. Shamberger --
impression of sorts and degrees of nutritional fats on colon melanoma / Bandaru S. Reddy --
Modulation of mammary tumor prevalence by means of nutritional fats and antioxidants : a mechanistic method / M. Margaret King, Junji Terao, Gemma Brueggemann, Paul B. McCay, and Robert A. Magarian --
Modulation of benzo[a]pyrene metabolism by way of nutritional sulfur amino acids / Edward L. Wheeler, Daniel E. Schwass, Ladell Crawford, and David L. Berry --
nutritional components affecting organic responses to esophageal and colon chemical carcinogenesis / Paul M. Newberne --
impact of nutrition on hormone-dependent cancers / Kenneth okay. Carroll --
Carcinogen-DNA binding : a explore for metabolic activation in vivo and in vitro / C. Anita, H. greater, and Anthony Dipple --
impression of nutrients at the metabolism and toxicity of mycotoxins / Johnnie R. Hayes --
nutrition and drug interactions / C. Jelleff Carr --
nutritional nutrition E and cigarette smoking / Ching ok. Chow --
impression of the antioxidant butylated hydroxyanisole on in vivo formation of benzo[a]pyrene metabolite-DNA adducts : correlation with inhibition of benzo[a]pyrene-induced neoplasia by means of butylated hydroxyanisole / Marshall W. Anderson, Peter I. Adriaenssens, Catherine M. White, Y.M. Ioannou, and Alan G.E. Wilson --
insufficient diet E and selenium nutrients : impression on enzymes linked to hydroperoxide metabolism / C. Channa Reddy, Craig E. Thomas, and Richard W. Scholz --
Selenium and carcinogenesis / John A. Milner --
In vitro results of soybean protease inhibitors / Jonathan Yavelow, Kenneth A. Beck, Mortimer Levitz, and Walter Troll --
nutritional protein and the carcinogenesis, metabolism, and toxicity of 1,2-dimethylhydrazine / Willard J. Visek and Steven ok. Clinton --
nutrients and experimental breast melanoma : the consequences of nutritional fats and protein / Steven ok. Clinton and Willard J. Visek --
advertising of liver carcinogenesis : interactions of barbiturates and a choline-deficient vitamin / H. Shinozuka, A.J. Demetris, S.L. Katyal, and M.I.R. Perera --
Modulation of chemical mutagenesis in a Salmonella/mammalian tissue bioassay through nutrition A and different retinoids / Malcolm B. Baird --
results of hormone and nutrition on hepatic enzymes / Olga Greengard.
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Additional info for Xenobiotic Metabolism: Nutritional Effects
Example text
Reproduced with permission from Ref. 27. ch004 benzene with the greatest, l e a s t , and intermediate i n animals fed NIH-07, AIN-76A, and AIN-76A containing 5% pectin, respectively (Table IV). There were no s i g n i f i c a n t d i e t - r e l a t e d differences i n t o t a l v i a b l e anaerobic or aerobic bacteria i n the lumenal contents of the stomach or small i n t e s t i n e (Table IV). As with the DNT studies, there were no d i e t - r e l a t e d e f f e c t s on the r e l a t i v e proport i o n of each of the species present (data not shown).
Lewisohn, R. Science 1945, 101, 46. 12. , Leuchtenberger, R. ; Academic Press: New York, 1983, pp. 131-148. 13. G. Science 1947, 106, 619-621. 14. Herbert, V. " Grune and Stratton, New York, 1959. ch003 15. Chanaran, I. " Blackwell Scientific, St. Louis, 1979. 16. , Herbert, V. Brit. J. Haemat. 1971, 20, 511-520. 17. Herbert, V. J. Clin. Invest. 1958, 37, 646-650. 18. H. Amer. J. Physiol. 1958, 195, 194-196. 19. H. Prog. Hemat. 1975, 9, 57. 20. S. , Ed. John Wiley and Sons: New York, 1982, pp 21.
There appear t o be one-way t r a n s p o r t systems t o remove o x i d i z e d f o l a t e s from the nervous system (22, 23) and t o remove v i t a m i n B-12 analogues from t h e body v i a the b i l e ( 2 4 ) . Some of the B-12 analogues p r e s e n t i n m u l t i v i t a m i n / m i n e r a l p r e p a r a t i o n s may b l o c k mammalian c e l l metabolism (25) and s i n c e they b l o c k normal c e l l metabolism, p o s s i b l y may UTbck m a l i g n a n t c e l l metabolism. F o r a number of y e a r s , R u s s i a n workers have been f e e d i n g analogues of v i t a m i n B-12 t o normal and m a l i g n a n t c e l l s and showing t h a t t h e s e analogues w i l l knock out B-12 metabolism (25a).