Detection methods for cynobacterial toxins by G. A. Codd

By G. A. Codd

Cyanobacteria, or blue-green algae, regularly happen in numerous water kinds in the course of the global. A excessive percentage of the cyanobacterial blooms and scums include powerful pollution. This quantity appears to be like on the program of organic, toxicological, biochemical and physicochemical thoughts in experiences of cyanobacterial pollution and at experimental tools that experience pointed out a minimum of 50 cyanobacterial compounds poisonous to vertebrates.

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Hum. , 1987, 153. 2. ' National Rivers Authority,Water Oualitv Series No. 2. NRA Anglian Region, Peterborough PE2 OZR, 1990,128 pp. 3. C. A. M. A. Codd, Toxicon, 1992,2,1165. 4. M. W. A. Andersen, S. E. Moore, R. Skulberg, Env. Tox. , 1992,Is,321. 5. K. , Darmstadt, 1967. 6. W. Blum and R. Aicholz, HRC&CC, 1990,& 515. 7. R. B. Y. Stainer, 'The prokaryots. A handbook on habitats, isolation and identification of bacteria', Springer-Verlag, Berlin, West Germany, 1981, p. 212. 8. R. M. Skulberg, 'Research with algal cultures - NIVAs culture collection of algae', ISBN 82-577-1743-6,Norwegian Institute for Water Research, Oslo, Norway, 1990.

Rlo, A p h a n i ~ o m e n o nand ~~~ Oscillatoria s ~I. ~ Anatoxin-a is a small alkaloid compound which acts as a po:;t-synaptic cholinergic depolarising agent". The symptoms include muscle fasciculation, loss of coordination, gasping, convulsions and death by respiratory arrest. An analogue of anatoxin-a with similar toxicity has been isolated from Oscillatoria formosa13. The less common anatoxin-a(s) has also been isolated from Anabaena flosThis is a phosphate ester which acts as an acetylcholinesterase inhibitor.

Reported the isolation and structure of five “,,O -thar had microcystizs from a strain of yicrocvstis aebeen isolaced from a hepatotoxic water bloom sample coilected in Lake Kroshnoseso, Karelia, Russia. a This paper presents the results of a toxicity investigation on water bloom samples collected in Dn:teper River bas22 reservoirs and in some water bodies of the European par: of Russia. Also included are results of toxicity ctsiing for a i\l. aeruainosa strain isolated fzox a Dnieper Rix;er water bloom.

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